Beaver Run Resort Breckenridge, Colorado United States
It is now becoming possible to investigate higher-order properties of signaling systems and cascades and to understand how apparently different molecular-level events can nonetheless produce signaling systems with similar properties. The incorporation of mathematical and computational modeling, and the adoption of synthetic biology approaches, are becoming important tools in this endeavor. To capture this exciting new synthesis, the symposium will focus on the relationship between molecular-level events and their higher-order behavior, comparing the properties of signaling systems in diverse species, including non-plant examples. The symposium will be structured around common signaling features, such as switching between on and off states, the control of specificity, robustness in an unstable environment, and modulation of the sensitivity of the system by its activity or by external factors.